Diagnostics of
Andropause
How does the doctor determine testosterone deficiency?
Many men suspect it — but they don't know it. They haven't felt truly fit for months or years, they sleep poorly, have less drive, less desire. But to turn a suspicion into a clear diagnosis, it takes more than a gut feeling: it takes a structured medical consultation and targeted lab testing.
On this page you will learn how the diagnosis of andropause proceeds — what the doctor asks, which tests are done and why a single lab value alone is never enough.



Why an accurate diagnosis is so important
Testosterone deficiency can hide behind many faces: exhaustion, mood swings, erectile problems, weight gain. But the same symptoms also arise from other causes — thyroid diseases, diabetes, depression or sleep apnea, for example.
A hasty diagnosis or self-medication with hormones is therefore risky. Careful diagnostics protect you — and are the basis of every good treatment decision.
At AndroKlinik, we combine a structured initial consultation with a comprehensive laboratory panel. So that you enter the consultation optimally prepared, you will automatically receive a link to your personal medical history form after booking — to fill out at your leisure at home. Only when the questionnaire and lab values show a clear picture will next steps be discussed.
The diagnostic process at AndroKlinik: step by step
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Medical history form in advance
(via link)After booking, you will automatically receive a personal link to your medical history form — conveniently fillable from home and to be returned to us before the appointment. This way, the doctor can already know your situation before the consultation begins. -
Video consultation30–45 minutes with the specialist: your symptoms, your history, your questions. Based on the consultation, the doctor creates the individual lab order.
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Blood sampling close to homeYou visit a partner lab near you (Synlab, Labor MVZ, etc.) — no long journey, no appointment chaos. The standard panel covers all relevant hormone levels.
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Results evaluationWithin 48 hours, the specialist evaluates your lab values and explains them to you in a second video consultation — with concrete next steps.
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Treatment plan
If there is a need for treatment, you will receive an individual, written treatment plan. A private prescription can be issued directly as an e-prescription.
Book an initial consultation now
Video consultation with the andrologist — incl. lab order and results evaluation.
The medical consultation: what to expect
What the doctor will ask about:
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Which symptoms exist, since when and how severe
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General health status and pre-existing conditions
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Current medications (some can influence hormone levels)
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Lifestyle habits: sleep, diet, exercise, stress, alcohol
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Sexual health and satisfaction
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Family planning and desire to have children
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Previous hormone diagnostics or therapy
The AMS questionnaire: making symptoms measurable
To assess the severity of complaints, many andrologists use the internationally recognized AMS questionnaire (Aging Males' Symptoms Scale). It captures 17 typical symptoms and makes them comparable. At AndroKlinik, this questionnaire is part of the medical history form that you receive via link before your first video consultation — so the doctor already has your information available and can tailor the consultation specifically to your situation.
Here is a simplified overview of the areas covered — as a preview of what awaits you in the medical history form. Please note: the completed form is a valuable basis for discussion, but does not replace a medical assessment.
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Symptom |
None |
Mild |
Moderate |
Severe |
Very severe |
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Decline in general well-being |
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Joint and muscle pain |
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Excessive sweating / hot flashes |
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Sleep problems |
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Increased need for sleep / frequent tiredness |
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Irritability / nervousness |
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Anxiety / inner restlessness |
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Declining physical performance |
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Decline in muscle strength |
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Depressive mood |
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Feeling of having passed the peak of life |
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Decline in potency / erection |
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Decrease in frequency of morning erections |
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Decline in libido / sexual desire |
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The hormone lab: which values are measured?
A blood test alone does not make a diagnosis — but it can't be done without it. The crucial point: a complete hormone panel should be taken, not just a single testosterone value.
Why? Because testosterone exists in a complex balance in the body. Only when you know all the influencing factors can you correctly assess what is going on.
We analyze a great many values (you will receive a detailed list by email). Here is a small selection of blood values that you may have heard of in connection with andropause:
Important: when should blood be taken?
- Testosterone follows a daily rhythm: the values are highest in the morning.
- Recommendation: blood sampling while fasting, between 7:00 and 10:00 in the morning.
- No physical exertion on the day before the sampling.
- In case of abnormal values: repeat measurement on another day for confirmation.
|
Value |
Meaning |
Normal range (orientation) |
Why important? |
|---|---|---|---|
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Total testosterone |
The total volume of the hormone in the blood |
12–35 nmol/l (adults) |
Baseline value – but often not meaningful on its own |
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Free testosterone |
The biologically active, directly effective portion |
0.2–0.6 nmol/l |
Decisive: what is actually available to the body |
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SHBG |
Transport protein that binds testosterone |
10–70 nmol/l |
High SHBG = less free testosterone despite normal total values |
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LH |
Signal from the brain to the testes to produce |
1.5–9.3 IU/l |
Shows whether the hormone system regulates correctly |
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FSH |
Controls sperm production |
1.5–12.4 IU/l |
Relevant for desire to have children and testicular health |
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PSA |
Prostate-specific antigen |
< 4.0 ng/ml (up to age 50) |
Safety check before any hormone therapy |
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Blood count |
General health status, hematocrit |
Lab-specific |
Under TRT, hematocrit can rise – important check |
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Thyroid (TSH) |
Regulates energy metabolism |
0.4–4.0 mIU/l |
Thyroid disorders often imitate andropause symptoms |
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Metabolic (glucose, HbA1c, cholesterol) |
Metabolic health |
Lab-specific |
Overweight and diabetes accelerate testosterone decline |
All normal ranges are orientation values. The interpretation is always done in the clinical context — by the specialist, not by the lab sheet alone.
Your lab value check with the specialist
We organize blood sampling, evaluation and treatment plan —
all from a single source, nationwide via telemedicine.
Differential diagnoses
What else could be behind it?
A responsible andrologist never considers the symptom picture in isolation. Various diseases can cause symptoms similar to testosterone deficiency — or exist simultaneously:
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Possible cause |
Why it comes into question |
|---|---|
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Depression |
Similar symptoms: lack of drive, low mood, loss of libido – but can also be partly caused by testosterone deficiency |
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Hypothyroidism (underactive thyroid) |
Exhaustion, weight gain and sensitivity to cold overlap strongly with andropause symptoms |
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Sleep apnea |
Poor sleep directly lowers testosterone – and causes daytime tiredness and concentration problems |
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Diabetes / metabolic syndrome |
Insulin resistance inhibits testosterone production – overweight intensifies the effect |
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Primary hypogonadism |
Malfunction of the testes themselves – not age-related, recognizable by high LH with low testosterone |
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Hyperprolactinemia |
Elevated prolactin (e.g. due to medications or a pituitary tumor) inhibits testosterone production |
Frequently asked questions about andropause diagnostics
Home tests for testosterone are available, but for good reason are no substitute for a medical diagnosis. They usually only measure a single value, at a random time, without clinical context. Results can fluctuate greatly and lead to erroneous conclusions — in both directions.
Clarity begins with a conversation
Book your initial consultation now — specialist, discreet and without long waiting times.
About the author
Dr. med. Timo A. Spanholtz
Specialist in Plastic and Aesthetic Surgery - Specialist for Men's Health and Intimate Surgery
